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jeudi 3 octobre 2013

Shift work linked to fertility problems in new study

Millions of women in the United States are shift workers, following schedules that are beyond the typical 9 to 5, but little is known about how their hours can affect their reproductive health and fertility.

Now, a surprising new review of previous studies suggest that shift work can take a serious toll.

According to a study presented at the annual meeting of the European society of human reproduction and Embryology in London this week, women who work irregular shifts are more likely to experience reduced fertility and increased menstrual disturbance. Women who work nights may specifically have an increased risk of miscarriage.

"Nobody who works shifts has changes in biological function, and could be one of a number of things which has an impact on the ability of women to play," Dr. Linden Stocker, researcher at the University of Southampton in the United Kingdom, told The Huffington Post.

Stocker and colleagues reviewed 14 published studies between 1969 and 2013 that investigates the links between shifts and spontaneous abortions, menstrual disorders (defined as cycles of less than 24 days and cycles of 32 or more days) and not get pregnant after a year of trying of. All together, the studies included nearly 120,000 women.

Irregular schedule - Stocker defined as anything out of 8 to 18 - was linked to an increased rate of 33 per cent of menstrual disorders and one rate higher than 80 percent of Subfertility.

Working nights was not particularly tied to menstrual problems or problems getting pregnant, but was linked to an increased risk of miscarriage.

The researchers described the results as the novel, but warned that it should not be oversold. "We have not shown causality; We have found an association, warned the Stocker.

The women who work irregular shifts or nights can participate in any number of behaviors that could be influencing reproductive outcomes. For example, working hours is often linked to loss of sleep, decrease of exercise and poor diet.

But a growing body of research suggests that the physiological changes that accompany the work shift may be the culprits and that reproductive problems are a direct result of interrupted circadian rhythms.

In a preliminary study published last year, researchers manipulated the patterns of light and dark mice were exposed to it to test what effect, if any, this would have on their fertility. A group of mice subjected to repeated changes in its cycle of light / darkness had a success rate of pregnancy of just 22 per cent, compared to a success rate of 90 percent among a group of mice exposed to a typical day/night pattern.

"We were surprised, dramatically, the effect of manipulating the cycle was light-dark," said Keith Summa, researcher at Northwestern University and author in that study, in a statement. "We expected a negative effect of the disruption of the circadian clock, but not both."

Some estimates suggest that up to 15 million Americans take turns regular, including more and more women. According to the work of Sloan and research network of the family at Boston College, nearly one-third of companies with extended hours reported an increase in the number of workers by turns female in a 2004 study. Doctors and nurses often work irregular hours, as pilots, police officers, firefighters, employees of the restaurant and retail and home health aides.

Stocker said that women who work in shifts should not emphasize on the new findings, particularly until future studies have replicated the results.

"We know that many things can help improve reproductive outcomes - a balanced diet, exercise and take care of yourself in general," said. "While we hope that future studies prove or disprove our conclusions, it is important that women are focused on your health in general."

mardi 20 août 2013

Chlamydia Can Cause DNA Damage Linked With Cancer Risk, Study Finds

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By: Rachael Rettner, LiveScience Senior Writer
Published: 06/21/2013 12:17 PM EDT on LiveScience

Chlamydia infections can cause DNA damage that may increase the risk of later developing cancer, a new study suggests.

In the study, human cells growing in lab dishes that were infected with chlamydia were more likely to have DNA damage compared to cells not infected with chlamydia. What's more, this DNA damage was not always repaired properly by the cell, increasing the chances of genetic mutations.

Normally, cells with such DNA damage would activate a process that kills the cells, so that the cell does not turn cancerous. But in the study, the cells with DNA damage overrode this mechanism, and continued to divide. The continued division of cells with DNA mutations could eventually lead to cancer, the researchers said.

Earlier studies found an association between chlamydia infections and an increased risk of cervical and ovarian cancer in people, but such studies cannot prove cause and effect. The new study provides a biological explanation for how chlamydia could increase the risk of cancer.

However, because the study was conducted in cells in a lab dish, more research is needed to show the same thing occurs in people.

The new study, conducted by researchers at the Max Planck Institute for Infection Biology in Berlin, was published June 12 in the journal Cell Host & Microbe.

Chlamydia is a sexually transmitted disease caused by the bacteria Chlamydia trachomatis. Most infected people have no symptoms, according to the Centers for Disease Control and Prevention. However, untreated infections can damage the reproductive tract in women, and cause infertility. Complications from untreated infections are rare in men, but the condition can cause a burning sensation when urinating, and very rarely, prevent a man from fathering children, the CDC says.

Follow Rachael Rettner @RachaelRettner. Follow LiveScience @livescience, Facebook & Google+. Original article on LiveScience.com.

Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed. ]]> Also on HuffPost:

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vendredi 16 août 2013

Non-Maternal Urges Linked To Higher IQ In Controversial Study

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A British researcher made waves in the blogosphere this week after his study regarding maternal urges and intelligence was shared on the Internet.

Satoshi Kanazawa, an author and researcher at the London School of Economics and Political Science, suggested that the higher a woman's IQ, the lower her desire to reproduce, according to an article published in the Daily Mail.

The numbers dovetail with recent results from Britain's Office of National Statistics concluding more women than ever are deciding to remain childless, The Telegraph notes.

Kanazawa did not respond to a Huffington Post request for comment, so the exact nature of his study cannot be independently verified. However, he made very similar assertions in his 2012 book, The Intelligence Paradox: Why the Intelligent Choice Isn't Always the Smart One.

In a chapter called "Why intelligent people are the ultimate losers in life," Kanazawa notes that "more intelligent women are significantly more likely to remain childless -- and significantly less likely to become parents -- than less intelligent women."

According to Kanazawa, the "mean childhood IQ of women who have remained childless for life is 105.3, whereas the mean childhood IQ of women who have become parents is 101.7. The difference in mean childhood IQ between the two categories of women is very large and statistically significant."

The research is by no means unassailable, however.

Kanazawa uses statistics compiled from the U.K.'s National Child Development Study and measures intelligence based on IQ. This method is not foolproof, notes blog xoJane, which cites studies showing IQ is not the ultimate measure of intelligence.

There's also the matter of a past scandal involving a very controversial Kanazawa study that suggested black women are less attractive. After a backlash, Kanazawa was fired from his position at Psychology Today.

Finally, The Guardian's Sadhbh Walshe says Kanazawa appears to be making a troubling value judgment about women who choose not reproduce.

"It seems that this research is just adding fuel to the argument that women who don't have children, regardless of the reason, are not just selfish losers but dumb ones as well," Walshe writes, citing The Intelligence Paradox. "Kanazawa finds it paradoxical that intelligent women apparently don't possess the desire to pursue what should be the ultimate goal of their biological existence."

The concerns of many women -- not to mention mothers -- may be most accurately summed up by Al Arabiya columnist Ahlya Fateh.

Staring down the Daily Mail's examples of outspokenly "childless" women, including Cameron Diaz and Eva Mendes, Fateh jokes that her two children have caused her a fair share of stress and brain-cell loss and wonders if Kanazawa would consider her "sub-human on the intelligence scale."

On a more serious note, however, Fateh recounts the recent experience of her friend becoming a mother later in life.

"I received a text while I was in New York, 'He has arrived and I am so in love with him," Fateh wrote. "This told me everything I needed to know; there is a mother in all of us, she’s just waiting to be born and it doesn’t have a thing to do with her IQ."

She does, however, point out that she has "many friends who are unmarried and have chosen not to have children and are genuinely happy with their decisions."

vendredi 14 juin 2013

Organic Antioxidant Blend Recall: Frozen Berry Mix Sold At Costco Linked To Hepatitis A

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WASHINGTON — An Oregon company is recalling a frozen berry mix sold to Costco and Harris Teeter stores after the product was linked to at least 34 hepatitis A illnesses in five states.

The Food and Drug Administration said Tuesday that Townsend Farms of Fairview, Ore., is recalling its frozen Organic Antioxidant Blend, packaged under the Townsend Farms label at Costco and under the Harris Teeter brand at those stores.

Illnesses were reported in Colorado, New Mexico, Nevada, Arizona and California. Hawaii health officials are also investigating three cases of hepatitis A in people who have eaten the frozen berry product.

The recall came three days after the FDA and the federal Centers for Disease Control first announced a suspected link between the berries and the illnesses. The agency did not say why there was not an immediate recall.

Costco has stores across the country, while Harris Teeter stores are in eight East Coast states and the District of Columbia. Both grocery chains have said they have pulled the product from store shelves.

Hepatitis A is a contagious liver disease that can last from a few weeks to a several months. People often contract it when an infected food handler prepares food without appropriate hand hygiene. Food already contaminated with the virus can also cause outbreaks.

The FDA said it is inspecting the processing facilities of Townsend Farms. The CDC said the strain of hepatitis is rarely seen in North or South America but is found in the North Africa and Middle East regions.

Bill Gaar, a lawyer for Townsend Farms, said last week that the frozen organic blend bag includes pomegranate seeds from Turkey. The seeds are only used in the product associated with the outbreak and no other Townsend Farms products, he said.

"We do have very good records, we know where the (pomegranate seeds) came from, we're looking into who the broker is and we're sourcing it back up the food chain to get to it," Gaar said.

Hepatitis A illnesses occur within 15 to 50 days of exposure to the virus. Symptoms include fatigue, abdominal pain, jaundice, abnormal liver tests, dark urine and pale stool.

Vaccination can prevent illness if given within two weeks of exposure, and those who have already been vaccinated are unlikely to become ill, according to CDC.

CDC said the first illnesses were reported at the end of April. The same genotype of hepatitis A was identified in an outbreak in Europe linked to frozen berries this year, the CDC said, as well as a 2012 outbreak in British Columbia related to a frozen berry blend with pomegranate seeds from Egypt. In addition to the United States and Turkey, the agency said the Townsend Farms berries also included products from Argentina and Chile.

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Follow Mary Clare Jalonick on Twitter at http://twitter.com/mcjalonick